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Ohio State's 447-Case Mumps Outbreak Leaks Off Campus into Central Ohio

OHdisease outbreakadvisorymedium confidence
Confirmed Threat

Beginning in February 2014 (the first OSU case was identified around February 10-11, though Franklin County's earliest linked symptom onset was January 7), Ohio State University experienced a mumps outbreak that ultimately reached 447 central-Ohio cases — 155 OSU students, 31 OSU faculty/staff, and 54 community members linked to the university. OSU's Student Life Student Health Services issued repeated alerts urging students returning from spring break to monitor for symptoms, and Columbus Public Health declared a citywide outbreak. The vast majority of confirmed cases occurred in previously vaccinated individuals, illustrating the waning immunity that would later be observed at Harvard, Indiana, and Temple.

Alerts
2
Response
Killed
0
Injured
447
Institution
The Ohio State University
Public R1 · OH
~65,000 studentsBuckeye Alert / Student Life Student Health Services
Confirmed Timeline

Alert Sequence

2 messages in sequence

Some alert texts below are approximate reconstructions from news coverage, not confirmed verbatim transcripts. Reconstructed texts are shown in italic with a dashed border. Verified verbatim texts have a solid border and are marked accordingly.

INITIAL ALERTEmail
Mumps at Ohio State: What You Need to Know. Student Health Services has confirmed that there are several cases of mumps among Ohio State students. Mumps is a viral illness that causes fever, headache, muscle aches, fatigue, loss of appetite, and the characteristic swelling of the salivary glands (parotitis). Most students at Ohio State have been vaccinated against mumps with two doses of the MMR vaccine, which is highly protective — but no vaccine is 100% effective. As students return from spring break, we ask everyone to: (1) check your immunization records to confirm you have received two doses of MMR; (2) avoid sharing drinks, utensils, or anything that comes into contact with saliva; (3) wash your hands frequently; and (4) stay home and contact Student Health Services at 614-292-4321 if you develop symptoms. Anyone diagnosed with mumps will be asked to remain isolated for five days from the onset of swelling. We are working closely with Columbus Public Health to monitor and respond to this situation.

This text has been reconstructed from news coverage and may not reflect the exact original wording.

Reconstructed from the OSU BuckMD blog post 'You Got What!?! Mumps!?!' published March 12, 2014
March 12 timing is critical — OSU was actively trying to head off post-spring-break transmission, but the outbreak grew rapidly anyway
Phone number 614-292-4321 is the OSU Student Health Services main line
UPDATEEmail
Update on Mumps Outbreak: Columbus Public Health and Ohio State University are jointly responding to a mumps outbreak that has now grown to more than 230 cases in central Ohio. The outbreak began on the OSU campus and has now spread into the broader community. The majority of cases — both on and off campus — have occurred in individuals who were previously vaccinated, which is consistent with national patterns of mumps in the post-MMR era. We continue to urge: students with symptoms to isolate immediately and contact Student Health Services; anyone living, working, or socializing on or near campus to avoid sharing food, drinks, or anything that touches the mouth; and any student or staff member with documentation of fewer than two MMR doses to seek vaccination. Free MMR vaccinations are being offered at Columbus Public Health (240 Parsons Avenue) and at Student Health Services. We will continue to communicate updates as the situation evolves.

This text has been reconstructed from news coverage and may not reflect the exact original wording.

Reconstructed from CNN's late-April 2014 reporting that the outbreak had spread beyond OSU into central Ohio
240 Parsons Avenue is the verified address of Columbus Public Health's main clinic, which co-ran vaccination clinics with OSU
By the end of the outbreak, 97% of cases were in vaccinated individuals — a finding cited in subsequent CDC analysis of mumps in vaccinated populations
Context

Background

The 2014 Ohio State mumps outbreak became a foundational case in U.S. campus public health for two reasons: its scale (447 cases, the largest U.S. campus mumps outbreak in over a decade) and its demonstration that vaccinated populations remain susceptible to mumps in close-contact settings. The outbreak began in February 2014 with a small cluster of cases at OSU. By March 12, OSU's Student Health Services had begun warning students returning from spring break, with the BuckMD blog — written by OSU physicians — publishing public advisories. The outbreak grew rapidly: by late March, cases had spread off campus into central Ohio, prompting Columbus Public Health to declare a community-wide outbreak. By May 2014, over 360 cases had been confirmed in central Ohio, with the final tally reaching 447 by the end of the outbreak in August 2014. A striking feature of the outbreak: 97% of confirmed cases occurred in individuals who had been previously vaccinated against mumps. This pattern — first dramatically demonstrated at OSU — would later be observed at Harvard (2016), Indiana University (2016 and 2019), the University of Michigan, and Temple (2019), and is now understood to reflect waning of MMR-induced mumps immunity over time. CDC subsequently endorsed a third MMR dose in outbreak settings, a recommendation directly informed by the OSU experience.
Analysis

Key Findings

447 total cases — 155 OSU students, 31 faculty/staff, 54 community members linked to OSU, plus additional unlinked cases — the largest U.S. campus mumps outbreak in over a decade
97% of confirmed cases occurred in individuals who had previously received the MMR vaccine, demonstrating waning immunity
Outbreak spread off campus into central Ohio by late March 2014, prompting Columbus Public Health to declare a community-wide outbreak
Findings from this outbreak directly informed CDC's later recommendation for a third MMR dose in outbreak settings
Outcome
447 confirmed cases linked to OSU and central Ohio — 155 students, 31 OSU faculty/staff, 54 community members; rest were unaffiliated. No deaths. Columbus Public Health and OSU jointly ran multiple vaccination clinics. Outbreak ended August 2014.
Provenance

Sources

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Tags
mumpsdisease-outbreakpublic-healthvaccinationmmrohio-stateohiocolumbus-public-healthwaning-immunityspring-break
Added May 2026Updated May 2026Via ingestion